Pin1 Binding to Phosphorylated PSD-95 Regulates the Number of Functional Excitatory Synapses

The post-synaptic density protein 95 (PSD-95) plays a central role in excitatory synapse development and synaptic plasticity. Phosphorylation of the N-terminus of PSD-95 at threonine 19 (T19) and serine 25 (S25) decreases PSD-95 stability at synapses; however, a molecular mechanism linking PSD-95 ph...

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Detalles Bibliográficos
Autores principales: Delgado, Jary Y., Nall, Duncan, Selvin, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082786/
https://www.ncbi.nlm.nih.gov/pubmed/32231520
http://dx.doi.org/10.3389/fnmol.2020.00010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082786/
https://www.ncbi.nlm.nih.gov/pubmed/32231520
http://dx.doi.org/10.3389/fnmol.2020.00010

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