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Assessing the effect of genetic markers on drug immunogenicity from a mechanistic model-based approach

BACKGROUND: With the growth in use of biotherapic drugs in various medical fields, the occurrence of anti-drug antibodies represents nowadays a serious issue. This immune response against a drug can be due either to pre-existing antibodies or to the novel production of antibodies from B-cell clones...

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Detalles Bibliográficos
Autores principales:	Duhazé, Julianne, Caubet, Miguel, Hässler, Signe, Bachelet, Delphine, Allez, Matthieu, Deisenhammer, Florian, Fogdell-Hahn, Anna, Gleizes, Aude, Hacein-Bey-Abina, Salima, Mariette, Xavier, Pallardy, Marc, Broët, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082907/ https://www.ncbi.nlm.nih.gov/pubmed/32192445 http://dx.doi.org/10.1186/s12874-020-00941-z

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