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Comparison of RNA isolation methods on RNA-Seq: implications for differential expression and meta-analyses

BACKGROUND: The increasing number of transcriptomic datasets has allowed for meta-analyses, which can be valuable due to their increased statistical power. However, meta-analyses can be confounded by so-called “batch effects,” where technical variation across different batches of RNA-seq experiments...

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Detalles Bibliográficos
Autores principales: Scholes, Amanda N., Lewis, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082934/
https://www.ncbi.nlm.nih.gov/pubmed/32197587
http://dx.doi.org/10.1186/s12864-020-6673-2