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Advanced oxidation protein products induce microglia-mediated neuroinflammation via MAPKs-NF-κB signaling pathway and pyroptosis after secondary spinal cord injury

BACKGROUND: Inflammatory response mediated by oxidative stress is considered as an important pathogenesis of spinal cord injury (SCI). Advanced oxidation protein products (AOPPs) are novel markers of oxidative stress and their role in inflammatory response after SCI remained unclear. This study aime...

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Detalles Bibliográficos
Autores principales: Liu, Zhongyuan, Yao, Xinqiang, Jiang, Wangsheng, Li, Wei, Zhu, Siyuan, Liao, Congrui, Zou, Lin, Ding, Ruoting, Chen, Jianting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082940/
https://www.ncbi.nlm.nih.gov/pubmed/32192500
http://dx.doi.org/10.1186/s12974-020-01751-2