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Runt-related transcription factor 1 promotes apoptosis and inhibits neuroblastoma progression in vitro and in vivo

BACKGROUND: Runt-related transcription factor 1 (RUNX1) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters and can accelerate apoptosis in various tumors. However, the regulatory mechanisms underlying RUNX1 expression in neuroblastoma (NB), a highl...

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Detalles Bibliográficos
Autores principales: Hong, Mei, He, Jing, Li, Duo, Chu, Yuanyuan, Pu, Jiarui, Tong, Qiangsong, Joshi, Harish C., Tang, Shaotao, Li, Shiwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082942/
https://www.ncbi.nlm.nih.gov/pubmed/32197643
http://dx.doi.org/10.1186/s13046-020-01558-2