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Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammation via microglia phenotype modulation after traumatic brain injury

BACKGROUND: The interaction between astrocytes and microglia plays a vital role in the damage and repair of brain lesions due to traumatic brain injury (TBI). Recent studies have shown that exosomes act as potent mediators involved in intercellular communication. METHODS: In the current study, the e...

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Detalles Bibliográficos
Autores principales: Long, Xiaobing, Yao, Xiaolong, Jiang, Qian, Yang, Yiping, He, Xuejun, Tian, Weidong, Zhao, Kai, Zhang, Huaqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082961/
https://www.ncbi.nlm.nih.gov/pubmed/32192523
http://dx.doi.org/10.1186/s12974-020-01761-0