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Astrocyte-derived exosomes enriched with miR-873a-5p inhibit neuroinflammation via microglia phenotype modulation after traumatic brain injury
BACKGROUND: The interaction between astrocytes and microglia plays a vital role in the damage and repair of brain lesions due to traumatic brain injury (TBI). Recent studies have shown that exosomes act as potent mediators involved in intercellular communication. METHODS: In the current study, the e...
Autores principales: | Long, Xiaobing, Yao, Xiaolong, Jiang, Qian, Yang, Yiping, He, Xuejun, Tian, Weidong, Zhao, Kai, Zhang, Huaqiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082961/ https://www.ncbi.nlm.nih.gov/pubmed/32192523 http://dx.doi.org/10.1186/s12974-020-01761-0 |
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