Cargando…

Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer

Neurodegenerative disorders, including chemotherapy-induced cognitive impairment, are associated with neuronal mitochondrial dysfunction. Cisplatin, a commonly used chemotherapeutic, induces neuronal mitochondrial dysfunction in vivo and in vitro. Astrocytes are key players in supporting neuronal de...

Descripción completa

Detalles Bibliográficos
Autores principales: English, Krystal, Shepherd, Andrew, Uzor, Ndidi-Ese, Trinh, Ronnie, Kavelaars, Annemieke, Heijnen, Cobi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082981/
https://www.ncbi.nlm.nih.gov/pubmed/32197663
http://dx.doi.org/10.1186/s40478-020-00897-7