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Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer
Neurodegenerative disorders, including chemotherapy-induced cognitive impairment, are associated with neuronal mitochondrial dysfunction. Cisplatin, a commonly used chemotherapeutic, induces neuronal mitochondrial dysfunction in vivo and in vitro. Astrocytes are key players in supporting neuronal de...
Autores principales: | English, Krystal, Shepherd, Andrew, Uzor, Ndidi-Ese, Trinh, Ronnie, Kavelaars, Annemieke, Heijnen, Cobi J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082981/ https://www.ncbi.nlm.nih.gov/pubmed/32197663 http://dx.doi.org/10.1186/s40478-020-00897-7 |
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