FXR-mediated inhibition of autophagy contributes to FA-induced TG accumulation and accordingly reduces FA-induced lipotoxicity

BACKGROUND: Excessive dietary fat intake induces lipid deposition and contributes to the progress of nonalcoholic fatty liver disease (NAFLD). However, the underlying mechanisms are still unclear. METHODS: Yellow catfish were given two experimental diets with dietary lipid levels of 11.3 and 15.4%,...

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Detalles Bibliográficos
Autores principales: Wu, Kun, Zhao, Tao, Hogstrand, Christer, Xu, Yi-Chuang, Ling, Shi-Cheng, Chen, Guang-Hui, Luo, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082988/
https://www.ncbi.nlm.nih.gov/pubmed/32192487
http://dx.doi.org/10.1186/s12964-020-0525-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082988/
https://www.ncbi.nlm.nih.gov/pubmed/32192487
http://dx.doi.org/10.1186/s12964-020-0525-1

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