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FXR-mediated inhibition of autophagy contributes to FA-induced TG accumulation and accordingly reduces FA-induced lipotoxicity
BACKGROUND: Excessive dietary fat intake induces lipid deposition and contributes to the progress of nonalcoholic fatty liver disease (NAFLD). However, the underlying mechanisms are still unclear. METHODS: Yellow catfish were given two experimental diets with dietary lipid levels of 11.3 and 15.4%,...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082988/ https://www.ncbi.nlm.nih.gov/pubmed/32192487 http://dx.doi.org/10.1186/s12964-020-0525-1 |