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Acute Sleep Loss Upregulates the Synaptic Scaffolding Protein, Homer1a, in Non-canonical Sleep/Wake Brain Regions, Claustrum, Piriform and Cingulate Cortices

Homer proteins are a component of the post-synaptic density of neurons that are necessary for the maintenance and consolidation of behavioral state. The dominant negative protein homer1a is rapidly increased by neuronal activity and sleep loss. Homer1a knockout mice with globally absent homer1a have...

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Detalles Bibliográficos
Autores principales: Zhu, Jingxu, Hafycz, Jennifer, Keenan, Brendan T., Guo, Xiaofeng, Pack, Allan, Naidoo, Nirinjini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083128/
https://www.ncbi.nlm.nih.gov/pubmed/32231514
http://dx.doi.org/10.3389/fnins.2020.00188