ANP32B Deficiency Protects Mice From Lethal Influenza A Virus Challenge by Dampening the Host Immune Response

Deciphering complex virus-host interactions is crucial for pandemic preparedness. In this study, we assessed the impact of recently postulated cellular factors ANP32A and ANP32B of influenza A virus (IAV) species specificity on viral pathogenesis in a genetically modified mouse model. Infection of A...

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Detalles Bibliográficos
Autores principales: Beck, Sebastian, Zickler, Martin, Pinho dos Reis, Vinícius, Günther, Thomas, Grundhoff, Adam, Reilly, Patrick T., Mak, Tak W., Stanelle-Bertram, Stephanie, Gabriel, Gülşah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083139/
https://www.ncbi.nlm.nih.gov/pubmed/32231671
http://dx.doi.org/10.3389/fimmu.2020.00450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083139/
https://www.ncbi.nlm.nih.gov/pubmed/32231671
http://dx.doi.org/10.3389/fimmu.2020.00450

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