Biochemical and biophysical characterisation of immunoglobulin free light chains derived from an initially unbiased population of patients with light chain disease

In light chain (LC) diseases, monoclonal immunoglobulin LCs are abundantly produced with the consequence in some cases to form deposits of a fibrillar or amorphous nature affecting various organs, such as heart and kidney. The factors that determine the solubility of any given LC in vivo are still n...

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Detalles Bibliográficos
Autores principales: Sternke-Hoffmann, Rebecca, Boquoi, Amelie, Lopez Y. Niedenhoff, David, Platten, Florian, Fenk, Roland, Haas, Rainer, Buell, Alexander K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083161/
https://www.ncbi.nlm.nih.gov/pubmed/32211238
http://dx.doi.org/10.7717/peerj.8771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083161/
https://www.ncbi.nlm.nih.gov/pubmed/32211238
http://dx.doi.org/10.7717/peerj.8771

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