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Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors

Non‐tuberculous mycobacterium (NTM) infections, such as those caused by Mycobacterium abscessus, are increasing globally. Due to their intrinsic drug resistance, M. abscessus pulmonary infections are often difficult to cure using standard chemotherapy. We previously demonstrated that a piperidinol d...

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Detalles Bibliográficos
Autores principales: de Ruyck, Jérôme, Dupont, Christian, Lamy, Elodie, Le Moigne, Vincent, Biot, Christophe, Guérardel, Yann, Herrmann, Jean‐Louis, Blaise, Mickaël, Grassin‐Delyle, Stanislas, Kremer, Laurent, Dubar, Faustine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083170/
https://www.ncbi.nlm.nih.gov/pubmed/32211280
http://dx.doi.org/10.1002/open.202000042