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Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors
Non‐tuberculous mycobacterium (NTM) infections, such as those caused by Mycobacterium abscessus, are increasing globally. Due to their intrinsic drug resistance, M. abscessus pulmonary infections are often difficult to cure using standard chemotherapy. We previously demonstrated that a piperidinol d...
Autores principales: | de Ruyck, Jérôme, Dupont, Christian, Lamy, Elodie, Le Moigne, Vincent, Biot, Christophe, Guérardel, Yann, Herrmann, Jean‐Louis, Blaise, Mickaël, Grassin‐Delyle, Stanislas, Kremer, Laurent, Dubar, Faustine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083170/ https://www.ncbi.nlm.nih.gov/pubmed/32211280 http://dx.doi.org/10.1002/open.202000042 |
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