Development of Photocrosslinking Probes Based on Huwentoxin-IV to Map the Site of Interaction on Nav1.7

Voltage-gated sodium (Nav) channels respond to changes in the membrane potential of excitable cells through the concerted action of four voltage-sensor domains (VSDs). Subtype Nav1.7 plays an important role in the propagation of signals in pain-sensing neurons and is a target for the clinical develo...

Descripción completa

Detalles Bibliográficos
Autores principales: Tzakoniati, Foteini, Xu, Hui, Li, Tianbo, Garcia, Natalie, Kugel, Christine, Payandeh, Jian, Koth, Christopher M., Tate, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083225/
https://www.ncbi.nlm.nih.gov/pubmed/31732432
http://dx.doi.org/10.1016/j.chembiol.2019.10.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083225/
https://www.ncbi.nlm.nih.gov/pubmed/31732432
http://dx.doi.org/10.1016/j.chembiol.2019.10.011

Ejemplares similares