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Minimum concentration of Amphotericin B in serum according to the formulation, dose, and daily or prolonged intermittent therapeutic regimen

INTRODUCTION: The therapeutic efficacy of daily amphotericin B infusion is related to its maximum concentration in blood; however, trough levels may be useful in intermittent regimens of this antifungal drug. METHODS: High performance liquid chromatography (HPLC) was used to determine the minimum co...

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Detalles Bibliográficos
Autores principales: Schiave, Leticia Aparecida, Nascimento, Erika, Gaspar, Gilberto Gambero, Vilar, Fernando Crivelenti, Martinez, Edson Zangiacomi, de Gaitani, Cristiane Masetto, Martinez, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083383/
https://www.ncbi.nlm.nih.gov/pubmed/32049198
http://dx.doi.org/10.1590/0037-8682-0463-2018