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Minimum concentration of Amphotericin B in serum according to the formulation, dose, and daily or prolonged intermittent therapeutic regimen
INTRODUCTION: The therapeutic efficacy of daily amphotericin B infusion is related to its maximum concentration in blood; however, trough levels may be useful in intermittent regimens of this antifungal drug. METHODS: High performance liquid chromatography (HPLC) was used to determine the minimum co...
Autores principales: | Schiave, Leticia Aparecida, Nascimento, Erika, Gaspar, Gilberto Gambero, Vilar, Fernando Crivelenti, Martinez, Edson Zangiacomi, de Gaitani, Cristiane Masetto, Martinez, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Medicina Tropical - SBMT
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083383/ https://www.ncbi.nlm.nih.gov/pubmed/32049198 http://dx.doi.org/10.1590/0037-8682-0463-2018 |
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