Cardiomyocyte‐derived exosomal microRNA‐92a mediates post‐ischemic myofibroblast activation both in vitro and ex vivo

AIMS: We hypothesize that specific microRNAs (miRNAs) within cardiomyocyte‐derived exosomes play a pivotal role in the phenoconversion of cardiac myofibroblasts following myocardial infarction (MI). METHODS AND RESULTS: We used an established murine model of MI, obtained in vivo via ligation of the...

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Detalles Bibliográficos
Autores principales: Wang, Xujun, Morelli, Marco Bruno, Matarese, Alessandro, Sardu, Celestino, Santulli, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083461/
https://www.ncbi.nlm.nih.gov/pubmed/31981320
http://dx.doi.org/10.1002/ehf2.12584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083461/
https://www.ncbi.nlm.nih.gov/pubmed/31981320
http://dx.doi.org/10.1002/ehf2.12584

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