Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death

Because of its key role in cancer development and progression, STAT3 has become an attractive target for developing new cancer therapeutics. While several STAT3 inhibitors have progressed to advanced stages of development, their underlying biology and mechanisms of action are often more complex than...

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Detalles Bibliográficos
Autores principales: Busker, S., Qian, W., Haraldsson, M., Espinosa, B., Johansson, L., Attarha, S., Kolosenko, I., Liu, J., Dagnell, M., Grandér, D., Arnér, E. S. J., Tamm, K. Pokrovskaja, Page, B. D. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083616/
https://www.ncbi.nlm.nih.gov/pubmed/32219156
http://dx.doi.org/10.1126/sciadv.aax7945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083616/
https://www.ncbi.nlm.nih.gov/pubmed/32219156
http://dx.doi.org/10.1126/sciadv.aax7945

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