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A worm gel-based 3D model to elucidate the paracrine interaction between multiple myeloma and mesenchymal stem cells

Multiple myeloma (MM) is a malignancy of terminally-differentiated plasma cells that develops mainly inside the bone marrow (BM) microenvironment. It is well known that autocrine and paracrine signals are responsible for the progression of this disease but the precise mechanism and contributions fro...

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Detalles Bibliográficos
Autores principales: Spelat, Renza, Ferro, Federico, Contessotto, Paolo, Warren, Nicholas J., Marsico, Grazia, Armes, Steven P., Pandit, Abhay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083757/
https://www.ncbi.nlm.nih.gov/pubmed/32211606
http://dx.doi.org/10.1016/j.mtbio.2019.100040