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sgRNA-PSM: Predict sgRNAs On-Target Activity Based on Position-Specific Mismatch
As a key technique for the CRISPR-Cas9 system, identification of single-guide RNAs (sgRNAs) on-target activity is critical for both theoretical research (investigation of RNA functions) and real-world applications (genome editing and synthetic biology). Because of its importance, several computation...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083770/ https://www.ncbi.nlm.nih.gov/pubmed/32199128 http://dx.doi.org/10.1016/j.omtn.2020.01.029 |