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Loss of copy of MIR1-2 increases CDK4 expression in ileal neuroendocrine tumors
Ileal neuroendocrine tumors (I-NETs) are the most common tumors of the small intestine. Although I-NETs are known for a lack of recurrently mutated genes, a majority of tumors do show loss of one copy of chromosome 18. Among the genes on chromosome 18 is MIR1-2, which encodes a microRNA, MIR1-3p, wi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083839/ https://www.ncbi.nlm.nih.gov/pubmed/32198354 http://dx.doi.org/10.1038/s41389-020-0221-4 |