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Single-molecule live-cell imaging visualizes parallel pathways of prokaryotic nucleotide excision repair

In the model organism Escherichia coli, helix distorting lesions are recognized by the UvrAB damage surveillance complex in the global genomic nucleotide excision repair pathway (GGR). Alternately, during transcription-coupled repair (TCR), UvrA is recruited to Mfd at sites of RNA polymerases stalle...

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Detalles Bibliográficos
Autores principales: Ghodke, Harshad, Ho, Han Ngoc, van Oijen, Antoine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083872/
https://www.ncbi.nlm.nih.gov/pubmed/32198385
http://dx.doi.org/10.1038/s41467-020-15179-y