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Dual regulation of p53 by the ribosome maturation factor SBDS

The Shwachman-Bodian Diamond syndrome (SBDS)-associated gene, SBDS, is involved in rRNA synthesis and ribosome maturation, but the role of SBDS in cancer is largely elusive. In this study, we found that SBDS is often overexpressed or amplified in human cancers, and high level of endogenous SBDS is s...

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Detalles Bibliográficos
Autores principales: Hao, Qian, Wang, Jieqiong, Chen, Yajie, Wang, Shanshan, Cao, Mingming, Lu, Hua, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083877/
https://www.ncbi.nlm.nih.gov/pubmed/32198344
http://dx.doi.org/10.1038/s41419-020-2393-4