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Iron dyshomeostasis, lipid peroxidation and perturbed expression of cystine/glutamate antiporter in Alzheimer’s disease: Evidence of ferroptosis

Iron dyshomeostasis is implicated in Alzheimer’s disease (AD) alongside β-amyloid and tau pathologies. Despite the recent discovery of ferroptosis, an iron-dependent form cell death, hitherto, in vivo evidence of ferroptosis in AD is lacking. The present study uniquely adopts an integrated multi-dis...

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Detalles Bibliográficos
Autores principales: Ashraf, Azhaar, Jeandriens, Jérôme, Parkes, Harold G., So, Po-Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083890/
https://www.ncbi.nlm.nih.gov/pubmed/32199332
http://dx.doi.org/10.1016/j.redox.2020.101494