Single-molecule imaging reveals molecular coupling between transcription and DNA repair machinery in live cells

The Escherichia coli transcription-repair coupling factor Mfd displaces stalled RNA polymerase and delivers the stall site to the nucleotide excision repair factors UvrAB for damage detection. Whether this handoff from RNA polymerase to UvrA occurs via the Mfd-UvrA(2)-UvrB complex or alternate react...

Descripción completa

Detalles Bibliográficos
Autores principales: Ho, Han Ngoc, van Oijen, Antoine M., Ghodke, Harshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083905/
https://www.ncbi.nlm.nih.gov/pubmed/32198374
http://dx.doi.org/10.1038/s41467-020-15182-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083905/
https://www.ncbi.nlm.nih.gov/pubmed/32198374
http://dx.doi.org/10.1038/s41467-020-15182-3

Ejemplares similares