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Single-molecule imaging reveals molecular coupling between transcription and DNA repair machinery in live cells
The Escherichia coli transcription-repair coupling factor Mfd displaces stalled RNA polymerase and delivers the stall site to the nucleotide excision repair factors UvrAB for damage detection. Whether this handoff from RNA polymerase to UvrA occurs via the Mfd-UvrA(2)-UvrB complex or alternate react...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083905/ https://www.ncbi.nlm.nih.gov/pubmed/32198374 http://dx.doi.org/10.1038/s41467-020-15182-3 |