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Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides

Despite evident regulatory roles of heparan sulfate (HS) saccharides in numerous biological processes, definitive information on the bioactive sequences of these polymers is lacking, with only a handful of natural structures sequenced to date. Here, we develop a “Shotgun” Ion Mobility Mass Spectrome...

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Detalles Bibliográficos
Autores principales: Miller, Rebecca L., Guimond, Scott E., Schwörer, Ralf, Zubkova, Olga V., Tyler, Peter C., Xu, Yongmei, Liu, Jian, Chopra, Pradeep, Boons, Geert-Jan, Grabarics, Márkó, Manz, Christian, Hofmann, Johanna, Karlsson, Niclas G., Turnbull, Jeremy E., Struwe, Weston B., Pagel, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083916/
https://www.ncbi.nlm.nih.gov/pubmed/32198425
http://dx.doi.org/10.1038/s41467-020-15284-y