NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance

Axon pathfinding is critical for nervous system development, and it is orchestrated by molecular cues that activate receptors on the axonal growth cone. Robo family receptors bind Slit guidance cues to mediate axon repulsion. In mammals, the divergent family member Robo3 does not bind Slits, but ins...

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Detalles Bibliográficos
Autores principales: Pak, Joseph S., DeLoughery, Zachary J., Wang, Jing, Acharya, Nischal, Park, Yeonwoo, Jaworski, Alexander, Özkan, Engin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083938/
https://www.ncbi.nlm.nih.gov/pubmed/32198364
http://dx.doi.org/10.1038/s41467-020-15211-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083938/
https://www.ncbi.nlm.nih.gov/pubmed/32198364
http://dx.doi.org/10.1038/s41467-020-15211-1

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