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A critical evaluation of methods to interpret drug combinations

Combination therapy is increasingly central to modern medicine. Yet reliable analysis of combination studies remains an open challenge. Previous work suggests that common methods of combination analysis are too susceptible to noise to support robust scientific conclusions. In this paper, we use simu...

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Detalles Bibliográficos
Autores principales: Twarog, Nathaniel R., Connelly, Michele, Shelat, Anang A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083968/
https://www.ncbi.nlm.nih.gov/pubmed/32198459
http://dx.doi.org/10.1038/s41598-020-61923-1