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Epistatic contributions promote the unification of incompatible models of neutral molecular evolution
We introduce a model of amino acid sequence evolution that accounts for the statistical behavior of real sequences induced by epistatic interactions. We base the model dynamics on parameters derived from multiple sequence alignments analyzed by using direct coupling analysis methodology. Known stati...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084075/ https://www.ncbi.nlm.nih.gov/pubmed/32123092 http://dx.doi.org/10.1073/pnas.1913071117 |