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Sonoselective transfection of cerebral vasculature without blood–brain barrier disruption

Treatment of many pathologies of the brain could be improved markedly by the development of noninvasive therapeutic approaches that elicit robust, endothelial cell-selective gene expression in specific brain regions that are targeted under MR image guidance. While focused ultrasound (FUS) in conjunc...

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Detalles Bibliográficos
Autores principales: Gorick, Catherine M., Mathew, Alexander S., Garrison, William J., Thim, E. Andrew, Fisher, Delaney G., Copeland, Caitleen A., Song, Ji, Klibanov, Alexander L., Miller, G. Wilson, Price, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084076/
https://www.ncbi.nlm.nih.gov/pubmed/32123081
http://dx.doi.org/10.1073/pnas.1914595117