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Sonoselective transfection of cerebral vasculature without blood–brain barrier disruption
Treatment of many pathologies of the brain could be improved markedly by the development of noninvasive therapeutic approaches that elicit robust, endothelial cell-selective gene expression in specific brain regions that are targeted under MR image guidance. While focused ultrasound (FUS) in conjunc...
Autores principales: | Gorick, Catherine M., Mathew, Alexander S., Garrison, William J., Thim, E. Andrew, Fisher, Delaney G., Copeland, Caitleen A., Song, Ji, Klibanov, Alexander L., Miller, G. Wilson, Price, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084076/ https://www.ncbi.nlm.nih.gov/pubmed/32123081 http://dx.doi.org/10.1073/pnas.1914595117 |
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