Downregulation of miR-34a Promotes Proliferation and Inhibits Apoptosis of Rat Osteoarthritic Cartilage Cells by Activating PI3K/Akt Pathway

OBJECTIVE: To elucidate the expression and function of miR-34a in rat osteoarthritic cartilage cells, and further to explore its mechanism. MATERIAL AND METHODS: Rat model of osteoarthritis was constructed and knee joint cartilage cells were isolated in vitro. Immunocytochemical staining was used fo...

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Detalles Bibliográficos
Autores principales: Tao, Haitao, Cheng, Lei, Yang, Ruixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084127/
https://www.ncbi.nlm.nih.gov/pubmed/32214804
http://dx.doi.org/10.2147/CIA.S241855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084127/
https://www.ncbi.nlm.nih.gov/pubmed/32214804
http://dx.doi.org/10.2147/CIA.S241855

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