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Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice

Background: Glaucoma is an optic neuropathy and involves the progressive degeneration of retinal ganglion cells (RGCs), which leads to blindness in patients. We investigated the role of the neuroprotective kynurenic acid (KYNA) in RGC death against retinal ischemia/reperfusion (I/R) injury. Methods:...

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Detalles Bibliográficos
Autores principales: Nahomi, Rooban B., Nam, Mi-Hyun, Rankenberg, Johanna, Rakete, Stefan, Houck, Julie A., Johnson, Ginger C., Stankowska, Dorota L., Pantcheva, Mina B., MacLean, Paul S., Nagaraj, Ram H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084183/
https://www.ncbi.nlm.nih.gov/pubmed/32151061
http://dx.doi.org/10.3390/ijms21051795