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The Fate of Th17 Cells is Shaped by Epigenetic Modifications and Remodeled by the Tumor Microenvironment

Th17 cells represent a subset of CD4+ T cells characterized by the master transcription factor RORγt and the production of IL-17. Epigenetic modifications such as post-translational histone modifications and DNA methylation play a key role in Th17 cell differentiation and high plasticity. Th17 cells...

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Detalles Bibliográficos
Autores principales: Renaude, Elodie, Kroemer, Marie, Loyon, Romain, Binda, Delphine, Borg, Christophe, Guittaut, Michaël, Hervouet, Eric, Peixoto, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084267/
https://www.ncbi.nlm.nih.gov/pubmed/32121394
http://dx.doi.org/10.3390/ijms21051673