Cargando…

The Fate of Th17 Cells is Shaped by Epigenetic Modifications and Remodeled by the Tumor Microenvironment

Th17 cells represent a subset of CD4+ T cells characterized by the master transcription factor RORγt and the production of IL-17. Epigenetic modifications such as post-translational histone modifications and DNA methylation play a key role in Th17 cell differentiation and high plasticity. Th17 cells...

Descripción completa

Detalles Bibliográficos
Autores principales:	Renaude, Elodie, Kroemer, Marie, Loyon, Romain, Binda, Delphine, Borg, Christophe, Guittaut, Michaël, Hervouet, Eric, Peixoto, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084267/ https://www.ncbi.nlm.nih.gov/pubmed/32121394 http://dx.doi.org/10.3390/ijms21051673

Ejemplares similares

Epigenetic Reprogramming of CD4(+) Helper T Cells as a Strategy to Improve Anticancer Immunotherapy
por: Renaude, Elodie, et al.
Publicado: (2021)

Chemokine switch regulated by TGF-β1 in cancer-associated fibroblast subsets determines the efficacy of chemo-immunotherapy
por: Vienot, Angélique, et al.
Publicado: (2022)

EMT is associated with an epigenetic signature of ECM remodeling genes
por: Peixoto, Paul, et al.
Publicado: (2019)

CD8(+) CD226(high) T cells in liver metastases dictate the prognosis of colorectal cancer patients treated with chemotherapy and radical surgery
por: Viot, Julien, et al.
Publicado: (2023)

Epigenetic Regulation of EMT (Epithelial to Mesenchymal Transition) and Tumor Aggressiveness: A View on Paradoxical Roles of KDM6B and EZH2
por: Lachat, Camille, et al.
Publicado: (2018)

Epigenetic Control of Autophagy in Cancer Cells: A Key Process for Cancer-Related Phenotypes
por: Peixoto, Paul, et al.
Publicado: (2019)

Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma
por: Hervouet, Eric, et al.
Publicado: (2018)

Investigation of the prognostic value of CD4 T cell subsets expanded from tumor-infiltrating lymphocytes of colorectal cancer liver metastases
por: Kroemer, Marie, et al.
Publicado: (2020)

EZH2 and KDM6B Expressions Are Associated with Specific Epigenetic Signatures during EMT in Non Small Cell Lung Carcinomas
por: Lachat, Camille, et al.
Publicado: (2020)

Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish
por: Jang, Hyo Sik, et al.
Publicado: (2021)

Epigenetic Modifications in Prostate Cancer Metastasis and Microenvironment
por: Zhang, Shouyi, et al.
Publicado: (2023)

Tissue-resident memory T cells in gastrointestinal cancer immunology and immunotherapy: ready for prime time?
por: Abdeljaoued, Syrine, et al.
Publicado: (2022)

Bone Remodeling: Histone Modifications as Fate Determinants of Bone Cell Differentiation
por: Yi, Sun-Ju, et al.
Publicado: (2019)

Autophagy is associated with a robust specific transcriptional signature in breast cancer subtypes
por: Grandvallet, Céline, et al.
Publicado: (2020)

From 1957 to Nowadays: A Brief History of Epigenetics
por: Peixoto, Paul, et al.
Publicado: (2020)

Yersinia remodels epigenetic histone modifications in human macrophages
por: Bekere, Indra, et al.
Publicado: (2021)

Regulation of epigenetic modifications in the head and neck tumour microenvironment
por: Liu, Huimin, et al.
Publicado: (2022)

Editorial: The interconnection between epigenetic modifications and the tumor microenvironment
por: He, Siyuan, et al.
Publicado: (2023)

The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models
por: Hervouet, Eric, et al.
Publicado: (2015)

Severe COVID-19 patients exhibit an ILC2 NKG2D(+) population in their impaired ILC compartment
por: Gomez-Cadena, Alejandra, et al.
Publicado: (2020)

Epigenetic mechanisms of Immune remodeling in sepsis: targeting histone modification
por: Wu, Dan, et al.
Publicado: (2023)

Peripheral Innate Lymphoid Cells Are Increased in First Line Metastatic Colorectal Carcinoma Patients: A Negative Correlation With Th1 Immune Responses
por: Loyon, Romain, et al.
Publicado: (2019)

Epigenetic resetting in the human germ line entails histone modification remodeling
por: Gruhn, Wolfram H., et al.
Publicado: (2023)

Stem cell fate and microenvironment
por: Triffitt, James T., et al.
Publicado: (2022)

Proximity Ligation In situ Assay is a Powerful Tool to Monitor Specific ATG Protein Interactions following Autophagy Induction
por: Gauthier, Thierry, et al.
Publicado: (2015)

Harnessing Antitumor CD4(+) T Cells for Cancer Immunotherapy
por: Ben Khelil, Myriam, et al.
Publicado: (2022)

The presence of senescent peripheral T-cells is negatively correlated to COVID-19 vaccine-induced immunity in cancer patients under 70 years of age
por: Orillard, E., et al.
Publicado: (2023)

Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications
por: Tian, Shengya, et al.
Publicado: (2019)

Shaping Up the Tumor Microenvironment With Cellular Fibronectin
por: Efthymiou, Georgios, et al.
Publicado: (2020)

Insights into the post-translational modification and its emerging role in shaping the tumor microenvironment
por: Li, Wen, et al.
Publicado: (2021)

Metabolites in the Tumor Microenvironment Reprogram Functions of Immune Effector Cells Through Epigenetic Modifications
por: Li, Yijia, et al.
Publicado: (2021)

Pan-cancer analysis based on epigenetic modification explains the value of HJURP in the tumor microenvironment
por: Li, Junwu, et al.
Publicado: (2022)

Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitis
por: Yang, Wen-Lan, et al.
Publicado: (2023)

The NMD Pathway Regulates GABARAPL1 mRNA during the EMT
por: Baudu, Timothée, et al.
Publicado: (2021)

Fates of CD8+ T cells in Tumor Microenvironment
por: Maimela, Nomathamsanqa Resegofetse, et al.
Publicado: (2018)

Correction: Insights into the post-translational modification and its emerging role in shaping the tumor microenvironment
por: Li, Wen, et al.
Publicado: (2022)

The DNMT1/PCNA/UHRF1 disruption induces tumorigenesis characterized by similar genetic and epigenetic signatures
por: Pacaud, Romain, et al.
Publicado: (2014)

Epigenetic control of embryonic stem cell fate
por: Christophersen, Nicolaj Strøyer, et al.
Publicado: (2010)

Epigenetic memory and cell fate reprogramming in plants
por: Birnbaum, Kenneth D., et al.
Publicado: (2017)

Multiple epigenetic modification profiles reveal the tumor immune microenvironment and clinical outcomes of uveal melanoma
por: Nan, Xinshuai, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_505vhn9mbuc5j6a0cu9hpc7a3a