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APP Maturation and Intracellular Localization Are Controlled by a Specific Inhibitor of 37/67 kDa Laminin-1 Receptor in Neuronal Cells

Amyloid precursor protein (APP) is processed along both the nonamyloidogenic pathway preventing amyloid beta peptide (Aβ) production and the amyloidogenic pathway, generating Aβ, whose accumulation characterizes Alzheimer’s disease. Items of evidence report that the intracellular trafficking plays a...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Antaripa, Limone, Adriana, Napolitano, Filomena, Cerchia, Carmen, Parisi, Silvia, Minopoli, Giuseppina, Montuori, Nunzia, Lavecchia, Antonio, Sarnataro, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084285/
https://www.ncbi.nlm.nih.gov/pubmed/32143270
http://dx.doi.org/10.3390/ijms21051738