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Nonsense Mutations in the Yeast SUP35 Gene Affect the [PSI(+)] Prion Propagation

The essential SUP35 gene encodes yeast translation termination factor eRF3. Previously, we isolated nonsense mutations sup35-n and proposed that the viability of such mutants can be explained by readthrough of the premature stop codon. Such mutations, as well as the prion [PSI(+)], can appear in nat...

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Detalles Bibliográficos
Autores principales: Trubitsina, Nina P., Zemlyanko, Olga M., Bondarev, Stanislav A., Zhouravleva, Galina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084296/
https://www.ncbi.nlm.nih.gov/pubmed/32121268
http://dx.doi.org/10.3390/ijms21051648