Liraglutide Suppresses Tau Hyperphosphorylation, Amyloid Beta Accumulation through Regulating Neuronal Insulin Signaling and BACE-1 Activity

Neuronal insulin resistance is a significant feature of Alzheimer’s disease (AD). Accumulated evidence has revealed the possible neuroprotective mechanisms of antidiabetic drugs in AD. Liraglutide, a glucagon-like peptide-1 (GLP-1) analog and an antidiabetic agent, has a benefit in improving a perip...

Descripción completa

Detalles Bibliográficos
Autores principales: Jantrapirom, Salinee, Nimlamool, Wutigri, Chattipakorn, Nipon, Chattipakorn, Siriporn, Temviriyanukul, Piya, Inthachat, Woorawee, Govitrapong, Piyarat, Potikanond, Saranyapin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084306/
https://www.ncbi.nlm.nih.gov/pubmed/32138327
http://dx.doi.org/10.3390/ijms21051725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084306/
https://www.ncbi.nlm.nih.gov/pubmed/32138327
http://dx.doi.org/10.3390/ijms21051725

Ejemplares similares