Local Delivery of Gemcitabine Inhibits Pancreatic and Cholangiocarcinoma Tumor Growth by Promoting Epidermal Growth Factor Receptor Degradation

Gemcitabine is clinically used to treat certain types of cancers, including pancreatic and biliary cancer. We investigated the signal transduction pathways underlying the local antitumor effects of gemcitabine-eluting membranes (GEMs) implanted in pancreatic/biliary tumor-bearing nude mice. Here, we...

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Detalles Bibliográficos
Autores principales: Jang, Sung Ill, Fang, Sungsoon, Baek, Yi-Yong, Lee, Don Haeng, Na, Kun, Lee, Su Yeon, Lee, Dong Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084314/
https://www.ncbi.nlm.nih.gov/pubmed/32111094
http://dx.doi.org/10.3390/ijms21051605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084314/
https://www.ncbi.nlm.nih.gov/pubmed/32111094
http://dx.doi.org/10.3390/ijms21051605

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