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Structural and Functional Characterization of New SsoPox Variant Points to the Dimer Interface as a Driver for the Increase in Promiscuous Paraoxonase Activity

Increasing attention is more and more directed toward the thermostable Phosphotriesterase-Like-Lactonase (PLL) family of enzymes, for the efficient and reliable decontamination of toxic nerve agents. In the present study, the DNA Staggered Extension Process (StEP) technique was utilized to obtain ne...

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Detalles Bibliográficos
Autores principales: Suzumoto, Yoko, Dym, Orly, Roviello, Giovanni N., Worek, Franz, Sussman, Joel L., Manco, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084321/
https://www.ncbi.nlm.nih.gov/pubmed/32121487
http://dx.doi.org/10.3390/ijms21051683