Cargando…

MicroRNA-24-3p Targets Notch and Other Vascular Morphogens to Regulate Post-ischemic Microvascular Responses in Limb Muscles

MicroRNAs (miRs) regulate complex processes, including angiogenesis, by targeting multiple mRNAs. miR-24-3p-3p directly represses eNOS, GATA2, and PAK4 in endothelial cells (ECs), thus inhibiting angiogenesis during development and in the infarcted heart. miR-24-3p is widely expressed in cardiovascu...

Descripción completa

Detalles Bibliográficos
Autores principales: Marchetti, Micol, Meloni, Marco, Anwar, Maryam, Al-Haj-Zen, Ayman, Sala-Newby, Graciela, Slater, Sadie, Ford, Kerrie, Caporali, Andrea, Emanueli, Costanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084374/
https://www.ncbi.nlm.nih.gov/pubmed/32138369
http://dx.doi.org/10.3390/ijms21051733