Cargando…
MicroRNA-24-3p Targets Notch and Other Vascular Morphogens to Regulate Post-ischemic Microvascular Responses in Limb Muscles
MicroRNAs (miRs) regulate complex processes, including angiogenesis, by targeting multiple mRNAs. miR-24-3p-3p directly represses eNOS, GATA2, and PAK4 in endothelial cells (ECs), thus inhibiting angiogenesis during development and in the infarcted heart. miR-24-3p is widely expressed in cardiovascu...
Autores principales: | Marchetti, Micol, Meloni, Marco, Anwar, Maryam, Al-Haj-Zen, Ayman, Sala-Newby, Graciela, Slater, Sadie, Ford, Kerrie, Caporali, Andrea, Emanueli, Costanza |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084374/ https://www.ncbi.nlm.nih.gov/pubmed/32138369 http://dx.doi.org/10.3390/ijms21051733 |
Ejemplares similares
-
EZH2 Modulates Angiogenesis In Vitro and in a Mouse Model of Limb Ischemia
por: Mitić, Tijana, et al.
Publicado: (2015) -
Local Inhibition of MicroRNA-24 Improves Reparative Angiogenesis and Left Ventricle Remodeling and Function in Mice With Myocardial Infarction
por: Meloni, Marco, et al.
Publicado: (2013) -
p75(NTR)-dependent activation of NF-κB regulates microRNA-503 transcription and pericyte–endothelial crosstalk in diabetes after limb ischaemia
por: Caporali, Andrea, et al.
Publicado: (2015) -
miR-15a/-16 Inhibit Angiogenesis by Targeting the Tie2 Coding Sequence: Therapeutic Potential of a miR-15a/16 Decoy System in Limb Ischemia
por: Besnier, Marie, et al.
Publicado: (2019) -
Nerve growth factor gene therapy improves bone marrow sensory innervation and nociceptor-mediated stem cell release in a mouse model of type 1 diabetes with limb ischaemia
por: Dang, Zexu, et al.
Publicado: (2019)