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Sulfonamide Inhibition Studies of an α-Carbonic Anhydrase from Schistosoma mansoni, a Platyhelminth Parasite Responsible for Schistosomiasis

Schistosomiasis is a debilitating infection provoked by parasitic flatworms called schistosomes. The species Schistosoma mansoni is endemic in Africa, where it causes intestinal schistosomiasis. Recently, an α-carbonic anhydrase (CA, EC 4.2.1.1) was cloned and characterized from this organism and de...

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Detalles Bibliográficos
Autores principales: Angeli, Andrea, Pinteala, Mariana, Maier, Stelian S., Simionescu, Bogdan C., Da’dara, Akram A., Skelly, Patrick J., Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084386/
https://www.ncbi.nlm.nih.gov/pubmed/32155992
http://dx.doi.org/10.3390/ijms21051842