Cargando…

Regulation of Small GTPase Rab20 by Ikaros in B-Cell Acute Lymphoblastic Leukemia

Ikaros is a DNA-binding protein that regulates gene expression and functions as a tumor suppressor in B-cell acute lymphoblastic leukemia (B-ALL). The full cohort of Ikaros target genes have yet to be identified. Here, we demonstrate that Ikaros directly regulates expression of the small GTPase, Rab...

Descripción completa

Detalles Bibliográficos
Autores principales: Payne, Jonathon L, Song, Chunhua, Ding, Yali, Dhanyamraju, Pavan Kumar, Bamme, Yevgeniya, Schramm, Joseph W, Desai, Dhimant, Sharma, Arati, Gowda, Chandrika, Dovat, Sinisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084408/
https://www.ncbi.nlm.nih.gov/pubmed/32138279
http://dx.doi.org/10.3390/ijms21051718