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Regulation of Small GTPase Rab20 by Ikaros in B-Cell Acute Lymphoblastic Leukemia
Ikaros is a DNA-binding protein that regulates gene expression and functions as a tumor suppressor in B-cell acute lymphoblastic leukemia (B-ALL). The full cohort of Ikaros target genes have yet to be identified. Here, we demonstrate that Ikaros directly regulates expression of the small GTPase, Rab...
Autores principales: | Payne, Jonathon L, Song, Chunhua, Ding, Yali, Dhanyamraju, Pavan Kumar, Bamme, Yevgeniya, Schramm, Joseph W, Desai, Dhimant, Sharma, Arati, Gowda, Chandrika, Dovat, Sinisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084408/ https://www.ncbi.nlm.nih.gov/pubmed/32138279 http://dx.doi.org/10.3390/ijms21051718 |
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