Cargando…

Contributions of DNA Damage to Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common type of neurodegenerative disease. Its typical pathology consists of extracellular amyloid-β (Aβ) plaques and intracellular tau neurofibrillary tangles. Mutations in the APP, PSEN1, and PSEN2 genes increase Aβ production and aggregation, and thus cause ear...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Xiaozeng, Kapoor, Anil, Gu, Yan, Chow, Mathilda Jing, Peng, Jingyi, Zhao, Kuncheng, Tang, Damu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7084447/
https://www.ncbi.nlm.nih.gov/pubmed/32121304
http://dx.doi.org/10.3390/ijms21051666